C2 plays a critical role in the activation of both the classical and the lectin pathways of complement. It forms the proteolytic subunit of the C3 and C5 convertase of both pathways.
-70â„ƒ or below. Avoid freeze/thaw.
Normal human serum
>95% by SDS-PAGE
93,000 Da (1 chain)
>90% versus normal human serum standard
10 mM sodium phosphate, 145 mM NaCl, pH 6.0
None, 0.22 µm filtered.
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