Human C3d protein

Background:

C3d is derived from human C3 after a series of proteolytic cleavages. Surface-bound C3d and its precursors C3dg and iC3b are recognized by complement receptor 2 (CR2, CD21) present on mature B cells and follicular dendritic cells which use these ligands to stimulate phagocytosis and antigen presentation to cells of the adaptive immune system.

Storage:

-70℃ or below. Avoid freeze/thaw.

Source:

Normal human serum

Purity:

>95% by SDS-PAGE

Molecular Weight:

Size:

33,800 Da (single chain)

100 µg/vial 

Concentration:

1.0 mg/ml

Buffer:

10 mM Sodium phosphate, 145 mM NaCl, pH 7.3

Preservative:

None, 0.22 µm filtered