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Human C5 Protein

PE71141

$709.00

$709.00 per vial

More info

Background:

Human C5 is a naturally glycosylated (1.6%) polypeptide containing two disulfide-linked chains. C5 is essential for formation of the membrane attack complex (MAC) and is activated by all three pathways of complement activation. Each pathway of complement activation generates proteolytic enzyme complexes (C3/C5 convertases) which are bound to the target surface. These enzymes cleave a peptide bond in the larger alpha chain of C5 releasing the highly potent anaphylatoxin C5a (74 amino acids) and activating C5b.

Storage:

-70 C or below. Avoid freeze/thaw

Source:

Normal human serum

Activity:

Purity:

>80% versus normal human serum standard

>95% by SDS-PAGE

Molecular Weight:

Size:

190,000 Da (2 chains)

250 µg/vial

Concentration:

1.0 mg/mL

Buffer:

10 mM sodium phosphate, 145 mM NaCl, pH 7.2

Preservative:

None, 0.22 µm filtered

 

 

 

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