Cobra Venom Factor (CVF)

Background:

A major component of cobra venom is CVF which binds to the victim’s factor B and this is then activated by factor D forming CVF, Bb.  CVF, Bb is a serine protease specific for the victim’s C3 and often C5 as well.  The activity of this C3/C5 convertase is not affected by the complement regulatory proteins in blood and the complex is extremely stable.

Storage:

-70℃ or below. Avoid freeze/thaw

Source:

Normal human serum

Activity:

Purity:

>300 units 

>95% by SDS-PAGE

Molecular Weight:

Size:

146,000 Da (multiple chains and isoforms)

1.0 mg/vial 

Concentration:

1.0 mg/mL

Buffer:

10 mM sodium phosphate, 145 mM NaCl, pH 7.2

Preservative:

Remark:

None, 0.22 µm filtered

This product is only available in the U.S.A