Rabbit Polyclonal, Phosphospecific
ApplicationsE, WB, IHC
Species reactivityZf, X, H, M, B, Ck, D, Sh
Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
14-3-3 protein beta/alpha (14-3-3) is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. 14-3-3 binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. 14-3-3 binding generally results in the modulation of the activity of the binding partner. 14-3-3 is a negative regulator of osteogenesis. Recent work has demonstrated that the dimeric status of the 14-3-3 protein is regulated by site-specific serine phosphorylation.
14-3-3 protein beta/alpha; Prepronerve growth factor RNH-1; Protein kinase C inhibitor protein 1; KCIP-1; Ywhab
KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser58 of rat 14-3-3.
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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