14-3-3 ( Ser58 ) Antibody

$450.00
AB-A100002

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Host/TypeRabbit Polyclonal, PhosphospecificUnit0.1 mlIsotypeRabbit IgApplicationsE, WB, IHCSpecies reactivityZf, X, H, M, B, Ck, D, ShFormatEach vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified

More details



Host/Type

Rabbit Polyclonal, Phosphospecific

Unit

0.1 ml

Isotype

Rabbit Ig

Applications

E, WB, IHC

Species reactivity

Zf, X, H, M, B, Ck, D, Sh

Format

Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.

Description

14-3-3 protein beta/alpha (14-3-3) is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. 14-3-3 binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. 14-3-3 binding generally results in the modulation of the activity of the binding partner. 14-3-3 is a negative regulator of osteogenesis. Recent work has demonstrated that the dimeric status of the 14-3-3 protein is regulated by site-specific serine phosphorylation.


Alternate Names

14-3-3 protein beta/alpha; Prepronerve growth factor RNH-1; Protein kinase C inhibitor protein 1; KCIP-1; Ywhab

Accession No.

P35213

Antigen

KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser58 of rat 14-3-3.

Application Notes

E: 1:1,000
E: 1:1,000
WB: 1:1,000
IHC: 1:500

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.


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