Host/TypeMouse Monoclonal Unit0.1 ml IsotypeMouse IgG1ApplicationsWBSpecies reactivityHFormatEach vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. | DescriptionThe protein encoded by this gene is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.Tissue specificity: Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. High levels are seen in the placenta while low levels are seen in the liver. Alternate NamesBWS; WBS; p57; BWCR; KIP2; CDKN1C Accession No.Clonality3E3 AntigenPurified recombinant fragment of human CDKN1C expressed in E. coli. Application NotesWB: 1:500-1:2000 StorageStore at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
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