Host/TypeRabbit Polyclonal Unit0.1 mg IsotypeRabbit IgApplicationsE, WB, IHCSpecies reactivityH, M, RFormatEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. | DescriptionThe glucocorticoid receptor (GR) is a receptor for glucocornticoids (GC) and has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (cRE) and as a modulator of other transcription factors. GR affects inflammatory responses, as well as cellular proliferations and differentiation in target tissues. GR is cytoplasmic in the absence of ligand, and nuclear after ligand-binding. GR belongs to the nuclear hormone receptor (NR3) sub family. GR contains 1 nuclear receptor DNA- binding domain. Alternate NamesGlucocorticoid receptor; GR; Nuclear receptor subfamily 3 group C member 1; NR3C1; GRL Accession No.AntigenKLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human GR. Application NotesE: 1:500-1:1,000 WB: 1:200-1:500 IHC: 1:200-1:500
StorageStore at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
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