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Human Complement Factor P (Properdin)

PE71154

$706.00

More info

Background:

Factor P is a 53,000 dalton cationic protein that circulates in blood in the form of dimers, trimers and tetramers. It binds rapidly to C3b on surfaces where complement has begun to activate. Factor P binds most avidly to C3b, Bb the alternative pathway C3/C5 convertase, but also binds to C3b and C3b,B complex with lower affinity. Its primary function is to stabilize the C3b, Bb complex allowing increased alternative pathway activation.

Storage:

-70 C or below. Avoid freeze/thaw

Source:

Normal human serum

Activity:

Purity:

>70% versus normal human serum standard 

>95% by SDS-PAGE

Molecular Weight:

Size:

53,000 Da (single chain)

100 µg/vial

Concentration:

1.0 mg/mL

Buffer:

10 mM sodium phosphate, 145 mM NaCl, pH 7.3

Preservative:

None, 0.22 µm filtered

 

 

 

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