View larger

IL1 beta Antibody

ASA-B0999

$365.00

More info

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification 

interleukin 1, beta Polyclonal IgG Rabbit Rat ELISA Immunogen affinity purified.

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of rat IL1 beta (202-229aa DPKQYPKKKMEKRFVFNKIEVKTKVEFE), different from the related human sequence by five amino acids, and from the related mouse sequence by one amino acid.

Properties

Form

Lyophilized

Size

100 µg/vial

Contents

Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3. *carrier free antibody available upon request.

Concentration

Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration).

Storage

At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene

IL1B

Protein

Interleukin-1 beta

Uniprot ID

Q63264

Function

Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.

Tissue Specificity

Sub-cellular localization

Secreted. Note: The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.

Sequence Similarities

Aliases

Catabolin antibody|H1 antibody|Hematopoietin 1 antibody|IFN beta inducing factor antibody|IL 1 antibody|IL 1 beta antibody|IL 1B antibody|IL-1 beta antibody|IL1 BETA antibody|IL1B antibody|IL1B_HUMAN antibody|IL1F2 antibody|Interleukin 1 beta antibody|Interleukin 1 beta precursor antibody|Interleukin-1 beta antibody|LAF antibody|OAF antibody|Osteoclast activating factor antibody| OTTHUMP00000162031 antibody| Preinterleukin 1 beta antibody|Preinterleukin beta antibody|Pro interleukin 1 beta antibody

Application Details

Application Concentration* Species Validated Using**
ELISA 0.1-0.5μg/ml RatSandwich ELISA format

AssaySolution provides a series of assays reacted with primary antibodies. *Blocking peptide can be purchased at $65. Contact us for more information

© 2024 Novateinbio.com