SRY ( sex determining region Y )-box 2 Human Recombinant ( SOX2 Human )

SRY ( sex determining region Y )-box 2 Human Recombinant ( SOX2 Human )
$175.00

DescriptionSOX2 Human Recombinant produced in E.Coli is a single, non-glycosylated,polypeptide chain containing 208 amino acids (1-200 a.a.) and having a molecular mass of 23.1kDa. SOX2 protein is fused to a 8 amino acid His-Tag at C-terminus and
Formulation
The SOX2 solution contains 20mM Tris-HCl pH-8, 2mM DTT, 0.2M NaCl & 40% glycerol.
Purity
Greater than 90% as determined by SDS-PAGE.
Description
SOX2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 208 amino acids (1-200 a.a.) and having a molecular mass of 23.1kDa. SOX2 protein is fused to an 8 amino acid His-Tag at C-terminus and purified by standard chromatography.
Protein Background
SOX2 is a transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. SOX4 is important for early embryogenesis and for embryonic stem cell pluripotency.
Expression host
Escherichia Coli.
Synonyms
MCOPS3, ANOP3, MGC2413, SOX2, SRY (sex determining region Y)-box 2.
Reagent Appearance
Sterile filtered colorless solution.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino acid sequence
MYNMMETELK PPGPQQTSGG GGGNSTAAAA GGNQKNSPDR VKRPMNAFMV WSRGQRRKMA QENPKMHNSE ISKRLGAEWK LLSETEKRPF IDEAKRLRAL HMKEHPDYKY RPRRKTKTLM KKDKYTLPGG LLAPGGNSMA SGVGVGAGLG AGVNQRMDSY AHMNGWSNGS YSMMQDQLGY PQHPGLNAHG AAQMQPMHRY LEHHHHHH.

 

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