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Single Chain Cardiac Troponin I-C Recombinant ( scIC )
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Formulation | Each mg/ml of protein contains 50% glycerol. |
Purity | Greater than 85.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. |
Description | Recombinant Single Chain Cardiac Troponin I-C produced in E.Coli is a single, non-glycosylated, polypeptide chain having a molecular mass of 45kDa.The scIC is purified by proprietary chromatographic techniques. |
Protein Background | Troponin Complex is a heteromeric protein playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, Troponin I, Troponin T and TroponinC. Each subunit is responsible for part of Troponin Complex function. E.g. Troponin I inhibits ATP-ase activity of acto-myosin.Troponin T and Troponin Iare presented in cardiac muscles in different forms than in skeletal muscles. Purified subunits of rcTnI, rcTnC and rcTnT are recomplexed in vitro under appropriate conditions. |
Expression host | Escherichia Coli. |
Synonyms | Troponin I cardiac muscle, Cardiac troponin I, TNNI3, TNNC1, CMH7, RCM1, cTnI, CMD2A, MGC116817, Troponin C slow skeletal and cardiac muscles, TN-C, TNNC1, TNNC, TNC, CMD1Z. |
Reagent Appearance | Sterile Filtered colourless liquid formualtion. |
Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. |