TRAIL  Antibody View larger

TRAIL Antibody

ASA-B1909

$365.00

More info

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification 

tumor necrosis factor (ligand) superfamily, member 10 Polyclonal IgG Rabbit Human WB Immunogen affinity purified.

Immunogen

E.coli-derived human TRAIL recombinant protein (Position: W78-G281). Human TRAIL shares 68% amino acid (aa) sequence identity with mouse TRAIL.

Properties

Form

Lyophilized

Size

100 µg/vial

Contents

Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3. *carrier free antibody available upon request.

Concentration

Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration).

Storage

At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene

TNFSF10

Protein

Tumor necrosis factor ligand superfamily member 10

Uniprot ID

P50591

Function

Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.

Tissue Specificity

Widespread; most predominant in spleen, lung and prostate.

Sub-cellular localization

Membrane ; Single-pass type II membrane protein .

Sequence Similarities

Belongs to the tumor necrosis factor family.

Aliases

Apo 2 ligand antibody|Apo 2L antibody|Apo-2 ligand antibody|Apo-2L antibody|APO2L antibody|CD 253 antibody|CD253 antibody|CD253 antigen antibody|Chemokine tumor necrosis factor ligand superfamily member 10 antibody|Protein TRAIL antibody|TL 2 antibody|TL2 antibody|TNF Related Apoptosis Inducing Ligand antibody|TNF related apoptosis inducing ligand TRAIL antibody|TNF-related apoptosis-inducing ligand antibody|TNF10_HUMAN antibody|TNFSF 10 antibody|TNFSF10 antibody|TNFSF10 protein antibody|TRAIL antibody|TRAIL PEN antibody|Tumor necrosis factor (ligand) family member 10antibody|Tumor Necrosis Factor (ligand) Superfamily Member 10 antibody|Tumor necrosis factor apoptosis inducing ligand splice variant delta antibody|Tumor necrosis factor ligand superfamily member 10 antibody

Application Details

Application Concentration* Species Validated Using**
Western blot 0.1-0.5μg/ml HumanAssaySolutio's ECL kit

AssaySolution recommends Mouse Chemiluminescent WB Detection Kit (AKIT003B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information
Anti-TRAIL antibody, ASA-B1909--1.jpg
All lanes: Anti-TRAIL(ASA-B1909) at 0.5ug/ml
WB: Recombinant Human TRAIL Protein 0.5ng
Predicted bind size: 42KD
Observed bind size: 42KD

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